Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative dosing ...

Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

Please provide your email address to receive an email when new articles are posted on . Teriparatide administered through the RT-102 pill provided higher bioavailability than injection with no ...

(Beyond Pesticides, July 23, 2024) In analyzing the interactions between neonicotinoid pesticides (NNPs) and microplastics (MPs), a recent study in The Science of The Total Environment finds that ...

MELBOURNE, Australia, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Gelteq Limited (“Gelteq” or the “Company”), a clinical and science-based company specialising in gel-based oral delivery solutions, today ...

The role of nitric oxide (NO) in the genesis of cerebral malaria is controversial. Most investigators propose that the unfortunate consequence of the high concentrations of NO produced to kill the ...

The bioavailability of pantoprazole when administered as a suspension in sodium bicarbonate solution and as the oral tablet was studied. In an open-label, randomized, two-period crossover study, ...

Although efforts have been made to improve solubility, many poorly soluble drugs still reach the market. Peter Nielsen discusses new developments in solubilisation technology, which could help those ...

Negativity around processed foods does not tell the whole story according to a new paper published by the Institute of Food Technologists Processed food, especially ultra-processed foods (UPF) is, for ...

Vitamin absorption depends on many complex factors, including form and diet. The best form of vitamin supplement for you depends on your health and needs. Many different types of supplemental vitamins ...