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  1. Recent Advances on Cell Culture Platforms for In Vitro Drug …

    The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since establishing the 2D in …

  2. Organoid: Biomedical application, biobanking, and pathways to ...

    Sep 8, 2024 · Organoids are tiny stem cell-derived 3D in vitro cell culture systems mimicking the structural and functional aspects of the tissues in the human body and provide a means to …

  3. Recent Advances on Cell Culture Platforms for In Vitro Drug …

    Mar 10, 2023 · The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since …

  4. Cell Based Assays - Sartorius

    The development of protein-based therapeutics requires comprehensive product analysis. Complete characterization calls for the use of distinct and complementary methods, including …

  5. Understanding organoids | Abcam

    Wnt3a and R-spondin promote hepatic stem cell proliferation, allowing organoid-based liver research 10. With their potential to mimic liver disorders, liver organoids are emerging as a …

  6. Leveraging 3D cell culture and AI technologies for next …

    Apr 22, 2025 · This reduces attrition rates during the drug development procedure. Furthermore, 3D cell models have shown a high potential for application in precision medicine that enables …

  7. From gut to liver: organoids as platforms for next-generation ...

    Mar 26, 2025 · Traditional toxicological assessment relied heavily on 2D cell cultures and animal models of study, which were inadequate for the precise prediction of human response to …

  8. Three-Dimensional Culture System: A New Frontier in Cancer Research

    Jul 16, 2025 · The pursuit of novel therapies has encouraged the development of novel model approaches in cancer research, drug discovery processes, and stem cell therapies. In the last …

  9. 3D Cell Culture Platforms as Drug Development Tools

    Aug 23, 2021 · CDER researchers are investigating cell culture platforms that can supplant the need for animal testing or clinical trials in specific regulatory contexts.

  10. Engineering the next generation of cell-based therapeutics

    May 30, 2022 · Cell-based therapeutics are an emerging modality with the potential to treat many currently intractable diseases through uniquely powerful modes of action. Despite notable …